Consider the most likely diagnosis first, then rule out serious conditions Use the history and examination findings to guide your thinking Think about common presentations of common conditions Don't anchor on the first diagnosis that comes to mind Consider red flags that might indicate serious pathology Use pattern recognition but verify with systematic thinking Think about what additional tests might help confirm your diagnosis Consider the patient's age, gender, and risk factors Use differential diagnosis to organize your thinking Present your findings in a logical, structured manner Explain your reasoning process clearly Consider alternative diagnoses if initial treatment isn't working Use clinical guidelines and evidence-based medicine Think about immediate, short-term, and long-term management Always consider patient safety in your diagnostic approach